Tag Archives: DNA

[Report] Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution

A sequencing method can discriminate epigenetically modified cytosine nucleotides within embryonic stem cell DNA. Continue reading

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[Report] Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution

A sequencing method can discriminate epigenetically modified cytosine nucleotides within embryonic stem cell DNA. Continue reading

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Buried Since the Jurassic Era, Ocean Microbes Are Still ‘Barely Alive’

Opening the Sediment Core Hans Røy opens a sediment core. Continue reading

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Buried Since the Jurassic Era, Ocean Microbes Are Still ‘Barely Alive’

Opening the Sediment Core Hans Røy opens a sediment core. Continue reading

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Genes may influence body’s bacteria

Certain DNA variants associated with microbial types Continue reading

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Genes may influence body’s bacteria

Certain DNA variants associated with microbial types Continue reading

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[Report] Structural Basis for DNA Damage–Dependent Poly(ADP-ribosyl)ation by Human PARP-1

An enzyme that binds to damaged DNA undergoes a structural reorganization that enhances its catalytic activity. Continue reading

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[Report] Structural Basis for DNA Damage–Dependent Poly(ADP-ribosyl)ation by Human PARP-1

An enzyme that binds to damaged DNA undergoes a structural reorganization that enhances its catalytic activity. Continue reading

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[Perspective] Structural Biology: PARP-1 Activation—Bringing the Pieces Together

A model structure sheds light on how the PARP-1 protein is activated in DNA repair. Continue reading

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[Perspective] Structural Biology: PARP-1 Activation—Bringing the Pieces Together

A model structure sheds light on how the PARP-1 protein is activated in DNA repair. Continue reading

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